This volume brings together the latest advances in the understanding, diagnosis, and management of intractable epilepsies. Noted experts review cutting-edge research and its clinical implications, explore strategies for designing new drugs, and offer patient management guidelines for adults and children. Major sections identify the mechanisms and clinical features in each seizure type that distinguish controllable from intractable epilepsies. Chapters examine intensive care management of status epilepticus and factors determining short-term and long-term prognosis, including seizure type, etiology, and age of onset. Other patient management issues include differential diagnosis, predictors of intractability, neurophysiological and neuroimaging evaluation, and drug selection.