Ray Barone (Ray Romano) enjoys a successful career as a sportswriter, and has a stable, happy family life with a loving wife and three great kids. Unfortunately for Ray, he can't shake the attention of his overbearing parents who live across the street, but may as well reside in the Barone family residence, such is the frequency of their visits. Ray's parents love to meddle in his affairs, often with hilarious consequences. Meanwhile, Ray's loser brother Robert (Brad Garrett) also loves to drop by Ray's place to bemoan his failings in life at every opportunity, often causing exasperation among the beleaguered family.

Episodes comprise:
1. The Invasion
2. Driving Frank
3. The Sitter
4. Getting Even
5. The Visit
6. Halloween Candy
7. Moving Out
8. The Article
9. The Lone Barone
10. No Fat
11. The Apartment
12. The Toaster
13. Ping Pong
14. Pants On Fire
15. Robert's Date
16. Frank's Tribute
17. Cruising With Marie
18. Ray Home Alone
19. Big Shots
20. Move Over
21. The Getaway
22. Working Girl
23. Be Nice
24. Dancing With Debra
25. Robert Moves Back
26. How They Meet