Inspired by the best selling book by Greg Behrendt and Liz Tuccillo He's Just Not That Into You features a host of Hollywood stars including Ben Affleck, Drew Barrymore, Jennifer Aniston, Jennifer Connelly, Justin Long, Scarlett Johannsson and Kris Kristofferson.

Several young Baltimore residents have a tough time finding love. A bored wife contemplates leaving her inattentive husband. The reason he's inattentive? He's having an affair with another woman, who in turn is being pursued by a single guy who's got the hots for her. However, the single guy could find happiness with another woman who's obsessed with him if his attention wasn't focused elsewhere.