A typically bored, affluent Californian housewife's world of domestic oblivion careers off its axis when she develops a mystery illness that puts her at odds with every aspect of the world around her - cars, dry cleaners, hair perms and even the new couch! Gradually she develops nosebleeds, vomiting and breathing problems and finally collapses.

In a desperate search for what is 'safe', she opts for virtual isolation in a porcelain igloo in the Texas desert, where the inhabitants drag round oxygen cylinders and the therapists act like evangelical preachers. Injected with horror, comic touches and psychological suspense, Safe is a visionary tale of the future. Has Carol brought her sickness upon herself or is she made vulnerable by a world that is more dangerous than we or she understands?