It is late at night and raining heavily. Smoke shells fly in through the windows of a rickety building owned by a social group. A police force breaks into the building to search the dim rooms, only to find traces of a religious service. A drop of blood falls onto the protective goggle of an investigating police officer and the Task Force Unit discovers a pile of corpses. These cult followers were presumed to have committed mass suicide. The Unit also discovers a pregnant woman who they take to the hospital where a baby is born.

Enter the Soul Guardians : Hyeon-am, Father Park, and Joon-hoo. They lead a fight against devils who exploit human beings in their quest to rule the world. Seung-Hee, once offered as a sacrifice, appears now 20 years later as a fully-matured woman who can conceive the Devil's children. The battle between the Soul Guardians and the Devil himself is only just beginning...