Pilot: Prescription: Murder
Psychiatrist Roy Fleming and his wife are celebrating their anniversary when he is called to deal with a patient - Susan Hudson. On returning he has to soothe his angry wife with the promise of a trip to Acapulco. When Fleming's wife is found dead, Columbo is brought in to investigate and seeds of doubt are planted in his mind which typically he can not ignore.

2: Fade In To Murder
Ward Fowler, a star with a reputation for being difficult and demanding, seems always to get what he wants. However, he has a dark secret - which if it ever came out would destroy his life. A producer of his hit TV show - Claire Daley - discovers his secret and is blackmailing Ward, until one day in Canada when Ward thinks he at last has the opportunity to close the deal for good.

3: Double Shock
When their elderly, wealthy uncle, Clifford Paris, is about to marry a much younger woman, twin brothers Dexter and Norman believe that they are about to be written out of his will and lose out on their inheritance. Although they have not spoken to each other in years, the two brothers unite to hatch a plan to kill their fitness enthusiast uncle and inherit his fortune.