Darkspore has a very difficult and problem-ridden installation. It took me 2-3 hours to get it up and running. And don't assume because you buy the disk, you have the game: You have to download a ton of extra content before it will work.
The game itself is good fun and quite addictive. The graphics are very pleasant and it's fun running around shooting aliens with different, customisable heroes.
A couple of annoying things (apart from the install): There is no way to pause the game, and there are some glitches in the editor screens. Also, it forces you to go online (login) every time you start the game, regardless if you want to play single player or multi player.
Overall, a good game, slightly spoiled by a poor install and a few annoyances.